Question

Cyclohexanone forms cyanohydrin in good yield but 2 2 6-trimethylcyclohexanone does not

Answer 1

Answer:

Answer : cyclohexanone forms cyanohydrin in good yield because the ketonic group has very less steric hindrance at both the ortho position but 2,2,6 tri methyl cyclohexanone have high steric hindrance which reduces the attack from CN nucleophile.