Question

define alpha thalassemia?​

Answer 1

Answer:

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define alpha thalassemia_?

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Alpha (a) thalassemia: The a-thalassemias involve the genes HBA1 and HBA2, inherited in a Mendelian recessive fashion. There are two gene loci and so four alleles. It is also connected to the deletion of the 16p (short-arm) chromosome, a-Thalassemias result in decreased a-globin production, therefore, fewer alpha-globin chains are produced, resulting in an excess of B chains in adults and excess y chains in newborns. The excess ß chains form unstable tetramers (called Hemoglobin H or HbH of 4 beta chains) which have abnormal oxygen dissociation curves.

Answer 2

Answer:

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