define chain initiation in forming polypeptide chains
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define chain initiation in forming polypeptide chains_??
(1) Chain initiation: It requires 3 Initiation factors in prokaryotes and 9 Initiation factors in eukaryotes.
- Binding of mRNA with smaller subunit of ribosomes (30S/40S)
30S sub unit+mRNA 30S-mRNA complex
In eukaryotes, there is formation of 40S-mRNA complex.
- Binding of 30S-mRNA with tRNA Meth non-formylated methionine is attached with tRNA in eukaryotes and formylated in prokaryotes..
30S-mRNA complex + tRNA Met GTP 30S-mRNA-tRNA Met
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