define dose . describe various factors influencing dose
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Answer:
The term posology (Greek posos, how much; and logos, science) is the science of doses. All Pharmacopoeias prescribe the doses of drugs for internal use.
The dose is usually expressed as a range. The minimum dose or the lower limit of the dose is essential for eliciting an intended therapeutic response whereas the maximum dose or the higher limit of the dose is the amount of the drug substance that can be tolerated by an average individual.
These doses are prescribed for the guidance of the prescriber. The pharmacist is much concerned with the maximum limit of the doses which, if exceeded, may cause untoward effects in the patient. The actual dose of a drug is to be decided by the prescriber depending on patient’s age, sex, symptoms, his medication history and the factors like tolerance, idiosyncrasy, route of administration etc.
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