Question

define downs syndrome?​

Answer 1

Answer:

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define downs syndrome_?

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Down's syndrome: It was first described in 1866 by Langdon Down. The disorder develops due to trisomy of chromosome number 21. Trisomic condition arises due to the formation of n+1 male or female gamete by non-disjunction and the subsequent fertilisation by a normal (n) gamete. It is characterised by:

• Short stature
• Small round head
• Furrowed tongue
• Partially open mouth
• Broad palm with characteristic palm crease
• Many 'loops' on finger tips
• Big and wrinkled tongue
• Physical (underdeveloped gonads and genitals, loose jointedness), psychomotor and mental development is retarted.

Answer 2

a congenital condition characterized by a distinctive pattern of physical characteristics including a flattened skull, pronounced folds of skin in the inner corners of the eyes, large tongue, and short stature, and by some degree of limitation of intellectual ability and social and practical skills. It usually arises from a defect involving chromosome 21,