Define Glomerular Filtration Rate (GFR)
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Answer:
Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.
All blood in the body flows through the kidneys hundreds of times each day. The kidneys push the liquid part of blood through tiny filters (called nephrons), then reabsorb most of the fluid back into the blood. The fluid and waste products that the kidneys don't reabsorb are excreted as urine.
The rate of blood flow through the kidneys is the glomerular filtration rate, or GFR. (The glomeruli are microscopic bundles of blood vessels inside nephrons, and are crucial parts of the filtering system.) The glomerular filtration rate can't be measured directly -- that's where measuring creatinine and creatinine clearance comes in.
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