Chemistry, asked by atulmishra1007, 1 year ago

define Hoffman's bromamide reaction?

Answers

Answered by sami91
3
Hey there !

When an amide is treated with bromine in an aqueous or ethanolic solution of sodium hydroxide, degradation of amide takes place leading to the formation of primary amine. This reaction involving degradation of amide and is popularly known as Hoffmann bromamide degradation reaction. The primary amine thus formed contains one carbon less than the number of carbon atoms in that amide.

RCONH2 +Br2 + 4NaOH R-NH2 + Na2CO3 + 2NaBr + 2H2O

Hope it helps you !
Answered by FALAQSHEIKH
0

When an amide is treated with bromine in an aqueous or ethanolic solution of sodium hydroxide, degradation of amide takes place leading to the formation of primary amine. This reaction involving degradation of amide and is popularly known as Hoffmann bromamide degradation reaction. The primary amine thus formed contains one carbon less than the number of carbon atoms in that amide.

RCONH2 +Br2 + 4NaOH

R-NH2 + Na2CO3 + 2NaBr + 2H2O

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