Question

define insertional inactivation ​

Answer 1

Insertional inactivation is theinactivation of a gene upon insertionof another gene inside in its place or within its coding sequence. This video also explains the selection of recombinant colonies in selective antibiotic medium by insertional inactivation.

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Answer 2

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Insertional inactivation is a technique used in recombinant DNA technology. In this procedure, a bacteria carrying recombinant plasmids or a fragment of foreign DNA is made to insert into a restriction site inside a gene to resist antibiotics, hence causing the gene to turn non-functional or in an inactivated state.

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