Question

Define Mendelian disorders. Give two examples. *

Answer 1

Answer:

Sickle-cell anaemia

This is a type of autosomal recessive genetic disorder. According to Mendelian genetics, its inheritance pattern follows inheritance from two carrying parents. It is caused when the glutamic acid in the sixth position of the beta-globin chain of haemoglobin molecule is replaced by valine.

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Answer 2

Answer:

Disorder caused by alternation or mutation in the single genes.

example : sickle cell anemia.