Question

Define proto-oncogenes and explain.

Answer 1

Inactive cancer causing genes are called proto-oncogenes. Normal cells contains genes called proto-oncogenes which when activated under certain conditions causes cancer.

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Answer 2

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An oncogene is a gene that has the potential to cause cancer.

In tumor cells, they are often mutated or expressed at high levels.

Most oncogenes began as proto-oncogenes, normal genes involved in cell growth and proliferation or inhibition of apoptosis

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