Define RH Grouping in humans .
also includes points on the case of second RH+ child and RH- Mother .
Also describe the disease caused due to that + medical aid use to control it .
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Answers
Rh disease occurs during pregnancy. It happens when the Rh factors in the mom’s and baby’s blood don’t match. It may also happen if the mom and baby have different blood types.
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Rh disease occurs during pregnancy. It happens when the Rh factors in the mom’s and baby’s blood don’t match. It may also happen if the mom and baby have different blood types.
What causes Rh disease?
Each person has a blood type (O, A, B, or AB). Everyone also has an Rh factor (positive or negative).
The Rh factor is a protein on the covering of the red blood cells. If the Rh factor protein is on the cells, the person is Rh positive. If there’s no Rh factor protein, the person is Rh negative.
A baby may have the blood type and Rh factor of either parent, or a combination of both parents.
There can be a problem when an Rh negative mother has a baby with an Rh positive father. If the baby's Rh factor is positive, like his or her father's, this can be an issue if the baby's red blood cells cross to the Rh negative mother. When this happens, the mom becomes sensitized to Rh positive blood.
If the mother is Rh-negative, her immune system treats Rh-positive fetal cells as if they were a foreign substance. The mother's body makes antibodies against the fetal blood cells. These antibodies may cross back through the placenta into the developing baby. They destroy the baby's circulating red blood cells.
rh antigen is similar to one present in rhesus monkey .
if person have rh antigen on RBC then it considered as rh positive
if not present then rh negative
if we mix rh positive with negative one then it will forms a special antibodies against rh antigen therefore rh group should also be matched before blood transfusion.
lets we talk about case when mother is rh negative and foetus is rh positive
in this case mother produce antibodies against rh positive antigen during pasturation as blood mixed up .
in this case 1st baby is safe but if 2 nd baby is rh positive then its dangerous for 2nd baby as antibody against rh positive is already present inside mother and leads to a condition known as erythroblastosis foetalis
to prevent it anti rh antibodies is given to mother during pasturation of first baby