define split gene....
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interrupted gene (also called a split gene) is a gene that contains expressed regions of DNA called exons, split with unexpressed regions called introns (also called intervening regions). Exons provide instructions for coding proteins, which create mRNA necessary for the synthesis of proteins.
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The "split gene" theory by Periannan Senapathy is a theory of the origin of introns, long non-coding sequences in eukaryotic genes that intervene the exons.
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