Define toxin and preparation of diphtheria toxoid
Answers
Answer:
Toxin means a poison of plant or animal origin, especially one produced by or derived from microorganisms and acting as an antigen in the body.
Explanation:
The preparation of diphtheria toxoid by the methods of Glenny (2) and of Ramon (3) involves prolonged incubation at elevated temperatures and with minimal quantities of formalin, from 0.3 to 0.4 per cent, so carefully adjusted that, when detoxification has reached the desired stage, changes affecting the antigenic action will not take place. There are obvious advantages in avoiding this complicated procedure and in adopting one that would eliminate the formalin as soon as the product was satisfactorily detoxified.
Answer:
A toxoid is an inactivated or attenuated toxin. A toxin is a poison made by other organisms which can make us sick or kill us. In other words, a toxin is toxic. A toxin is both toxic and immunogenic. A toxoid is no longer toxic but it is still as immunogenic as the toxin from which it was derived.
Explanation:
Vaccine Preparations
Vaccine Preparations Diphtheria toxoid is prepared by formaldehyde treatment of toxin and is standardized for potency according to the U.S. Food and Drug Administration. Toxoid is adsorbed to aluminum salts, which enhances immunogenicity.