Dehydrated amniotic membrane for vaginal reconstruction
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To assess the anatomical and functional results of neovagina creation with amniotic membrane. Methods: We operated on three young women with vaginal agenesis of whom two had a diagnosis of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and the other mixed gonadal dysgenesis. The mean age was 29.67 years (range 28-33). A fresh amniotic membrane retrieved from a Cesarean section on the same operation date was prepared over a mould and inserted into the newly formed tunnel between bladder and rectum as per McIndoe technique. The patients were followed up for one year minimum. Results: Mean vaginal depth achieved was 7.7 cm. Two patients expressed having satisfactory sexual life at follow-up interview. One patient needed further follow-up in clinic and self-dilation. Conclusions: McIndoe vaginoplasty with fresh-homologous amniotic membrane is a low-risk effective procedure. It can produce good result in fairly short time span with modest demand on patient compliance and rare morbidity Keywords: Vaginal reconstruction; Mayer-Rokitansky-Küster-Hauser; Vaginoplasty; Genital tract abnormality; Müllerian agenesis; Neovagina