Deletion of nucleotides which are not in the miltiple of three leading towhole change in whole frame. Such mutation are called
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A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. ... The earlier in the sequence the deletion or insertion occurs, the more altered the protein.
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