Describe in detail time and dose dependent pharmacokinetics of drugs and its implications in the clinical use and dosage regiment design of such drugs.
Answers
Medication Therapy Management (MTM) was officially recognized by the US Congress in the Medicare Prescription Drug, Improvement, and Modernization Act of 2003.1 The objective of this act is to improve the quality, effectiveness, and efficiency of healthcare delivery including prescription drugs. An MTM program is developed in cooperation with pharmacists and physicians to optimize therapeutic outcomes through improved medication use. MTM provides consultative, educational, and monitoring services to patients to obtain better therapeutic outcomes from medications by the enhanced understanding of medication therapy, improved compliance, control of costs, and prevention of adverse events and drug interactions. MTM programs have been developed for specific practice areas such as elderly care, diabetes, and asthma (Barnett et al, 2009).