Question

Describe nondisjunction and the effect it can have on a human?

Answer 1

Nondisjunction: Failure of paired chromosomes to separate (to disjoin) during cell division, so that both chromosomes go to one daughter cell and none go to the other. Nondisjunction causes errors in chromosome number, such as trisomy 21 (Down syndrome) and monosomy X (Turner syndrome.

Answer 2

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Failure of paired chromosomes to separate (to disjoin) during cell division, so that both chromosomes go to one daughter cell and none go to the other. Nondisjunction causes errors in chromosome number, such as trisomy 21 (Down syndrome) and monosomy X (Turner syndrome).

☞ Nondisjunction forms abnormal number of chromosomes in the gametes. Nondisjunction causes human disorders in autosomes from chromosomes 1-22. The examples are Down syndrome or trisomy 21, an extra copy of chromosome 21. People with Down syndrome have 47 chromosome instead 46.

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