Describe the changes occur in prophase of mitosis (answer is needed according to 4 marks short question)
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Answer:
Mitosis is the process of equational cell division where daughter cells, so produced, contain an equal number of chromosomes as that in the parent cell. The various stages of mitosis in an animal cell are as follows:
(i) Prophase: It is the first stage of mitosis that is marked by the initiation of the condensation of chromosomal material. Each chromosome is composed of two chromatids, which are attached by the centromere. At the end of prophase, the mitotic spindle begins to form from the centrioles. The nuclear membrane and the nucleolus disappear completely by the end of this stage.
(ii) Metaphase: It is the second stage of mitosis in which the condensation of the chromosomal material and the spindle formation gets complete. The spindle fibres get attached to the kinetochores of the chromosomes and the chromosomes get aligned along the metaphase plate
(iii) Anaphase: It is the stage of mitosis where the centromere of the chromosomes split and the chromatids get separated. The contraction of the spindle fibres moves the sister chromatid apart, towards the two opposite poles.
(iv) Telophase: It is the last stage of mitosis. In this stage, chromosomes finally reach their respective poles. The spindle fibres disappear and the nuclear envelope reappears around the chromosome cluster. Also, the nucleolus, Golgi complex, endoplasmic reticulum, and other cell organelles re-appear.