Question

Describe the important steps in muscle contraction.​

Answer 1

Answer:

The process of muscular contraction occurs over a number of key steps, including: Depolarisation and calcium ion release. Actin and myosin cross-bridge formation. Sliding mechanism of actin and myosin filaments.

Answer 2

Here's the Answer

Mechanism of muscle contraction is explainei by sliding filament theory which states that contraction of a muscle fibre takes place by the sliding of the thin filaments over the th’ ck filaments. As a nerve impulse reaches the terminal end of the axon, synaptic vesicles fuse with the axon membrane and release a chemical transmitter, acetylcholine and binds to receptor sites of the motor end plate. When depolarization of the motor end plate reaches a certain level, it creates an action potential. An action potential (impulse) passes from the motor end plate over the sarcolemma and then into the T-tubules and sarcoplasmic reticulum and stimulates the sarcoplasmic reticulum to release calcium ions into the sarcoplasm. The calcium ions bind to troponin causing a change in its shape and position. This in turn alters shape and the position of tropomyosin, to which troponin binds. This shift exposes the active sites on the F-actin molecules. Myosin cross-bridges are then able to bind to these active sites. The heads of myosin molecules project laterally from thick myofilaments towards the surrounding thin myofilaments. These heads are called cross bridges. The head of each myosin molecule contains an enzyme mysoin ATPase. In the presence of myosin ATPase,Ca++ and Mg++ ions, ATP breaks down into ADP and inorganic phosphate, releasing energy in the head. Energy from ATP causes energized myosin cross bridges to bind to actin.

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