Describe the mechanism of action of cry proteins
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Bacillus thuringiensis (Bt) insecticidal Cry toxins have been shown to be effective in controlling insect pests either in spray products or expressed in transgenic crops. ... The final pores induced by protoxin or by activated toxin have different characteristics, suggesting dual mode of action of Cry proteins.
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Their primary action is to lyse midgut epithelial cells by inserting into the target membrane and forming pores. Among this group of proteins, members of the 3-Domain Cry family are used worldwide for insect control, and their mode of action has been characterized in some detail.
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