Describe the mechanism of coagulation of blood
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Answer: Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. ... The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin.
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When there is an injury in the body, the injured tissue cells and platelets release thromboplastin (or thrombokinase). The inactive prothrombin then is converted into active thrombin by the calcium () ions. The activated thrombin now converts the soluble fibrinogen in the blood to insoluble fibrin. The fibrin and the erythrocytes (red blood cells ) then form a clot on the injured part.
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