Describe the process of transport of Oxygen (O2) in the human body. Add a note on oxygen dissociation curve and the factors affecting the curve.
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i) Oxygen enters the blood from the lungs and carbon dioxide is expelled out of the blood into the lungs.
ii) The blood serves to transport both gases.
iii) Oxygen is carried to the cells.
iv) Carbon dioxide is carried away from the cells.
The oxygen dissociation curve plots the % saturation against the partial pressure of oxygen, and its contribution to the total oxygen content. This is an S shaped curve due to the alterations in hemoglobin's affinity for oxygen in response to other physiologic factors. Please note the dotted line at the bottom of the graph. This represents the dissolved O2. Dissolved O2 is a linear relationship to its partial pressure and results in a straight line.
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