Question

Describe the role of RAG-1 and RAG-2 in generation of antibody diversity.

Answer 1

Function. In the vertebrate immune system, each antibody is customized to attack one particular antigen (foreign proteins and carbohydrates) without attacking the body itself. ... RAG-1 and RAG-2 are proteins at the ends of VDJ genes that separate, shuffle, and rejoin the VDJ genes.