describe the sequence of the reactions of kreb's cycle.
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Answers
Answer:
Krebs cycle also known as citric acid cycle or TCA was discovered by Hans Krebs. ... Then, TCA generate ATP, 3NADH and FADH2 by series of reactions start from oxaloacetate and acetyl coA. TCA cycle will pass NADH or FADH2 into electron transport chain and the oxidative phosphorylation to generate ATP molecules.
Explanation:
The Krebs cycle, also known as the citric acid cycle or TCA cycle is a series of reactions that take place in the mitochondria resulting in oxidation of acetyl CoA to release carbon dioxide and hydrogen atoms that later lead to the formation of water.
This cycle is termed the citric acid cycle as the first metabolic intermediate formed in the cycle is citric acid.
This cycle is also termed tricarboxylic acid (TCA) because it was then not certain whether citric acid or some other tricarboxylic acid (g., isocitric acid) was the first product of the cycle. However, now it has been known that the first product is indeed citric acid and thus the use of this name has since been discouraged.
This cycle only occurs under aerobic conditions as energy-rich molecules like NAD+ and FAD can only be retrieved from their reduced form once they transfer electrons to molecular oxygen.
The citric acid cycle is the final common pathway for the oxidation of all biomolecules; proteins, fatty acids, carbohydrates. Molecules from other cycles and pathways enter this cycle through Acetyl CoA.
The citric acid cycle is a cyclic sequence of reactions formed of 8 enzyme-mediated reactions.
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This cycle is also particularly important as it provides electrons/ high-energy molecules to the electron transport chain for the production of ATPs and water.
Pyruvate formed at the end of glycolysis is first oxidized into Acetyl CoA which then enters the citric acid cycle.