Question

DGH IS PNH ________&_____&_____&




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Answer 1

Explanation:

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired, life-threatening disease of the blood. The disease is characterized by destruction of red blood cells (hemolytic anemia), blood clots (thrombosis), and impaired bone marrow function (not making enough of the three blood components).

Answer 2

PNH is caused when mutations of the PIG-A gene occur in a bone marrow stem cell. Stem cells give rise to all the mature blood elements including red blood cells (RBC), which carry oxygen to our tissues; white blood cells (WBC), which fight infection; and platelets (PLT), which are involved in forming blood clots.