Question

diff between leading and lagging strand????

Answer 1

leading strand: the DNA polymerase binds at the 3′ of the template strand and sinthesize from 5′ to 3′. Now since the sinthesis direction and the DNA unwinding direction is the same, the new strand will be sinthetized in one go. Since new single template strand will be available as the DNA polymerase advances on the strand.

Lagging strand: now the situation is different, since the DNA sinthesis and the unwinding direction will be opposite. So the DNA polymerase sinthesizes and then reaches a point that has not been unwinded yet and has to “wait”. When the DNA is unwinded, the DNA polymerase can continue sinthesizing till another stop point then it waits again and so on. So it won’t be sinthesized in one go, but pieces by pieces. So that’s why is reffered as lagging strand.

Answer 2

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➡LEADING STRAND:
A leading strand is the strand which is synthesized in the 5’-3’direction or the direction the same as the replication fork movement. 

➡LAGGING STRAND:
A lagging strand is the strand which is synthesized in the 3’-5’ direction or opposite direction as to the movement of the replication fork. 

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