Question

Difference between absolute and relative configuration

Answer 1

Answer:

Relative configuration: The position of atoms or groups in space in relation to (i.e., relative to) something else in the molecule. Compare with absolute configuration, which is independent of atoms or groups elsewhere in the molecule. Cis, trans, E, and Z are all designations of relative configuration.

Explanation:

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Answer 2

Answer:

An absolute configuration refers to the spatial arrangement of the atoms of a chiral molecular entity and its stereochemical description e.g. R or S, referring to Rectus, or Sinister, respectively. Absolute configurations for a chiral molecule are most often obtained by X-ray crystallography.

Relative configuration refers to the relationship between molecules or atoms.