difference between autosomal recessive trait and X-linked recessive trait.
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In autosomal recessive inheritance, both copies of the gene in each cell have mutations . The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. Autosomal recessive disorders are typically not seen in every generation of an affected family.
X-linked recessive disorders are also caused by mutations in genes on the X chromosome. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation would have to occur in both copies of the gene to cause the disorder (illustration). Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission).
X-linked recessive disorders are also caused by mutations in genes on the X chromosome. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation would have to occur in both copies of the gene to cause the disorder (illustration). Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission).
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(1) Autosomal traits are governed by the genes on chromosomes other than sex Chromosomes.example in humans there are 22 pairs of autosomal Chromosomes.
(2) Sex linked traits are governed by genes on sex Chromosomes. example in humans there is one pair of sex Chromosomes, in female it is XX and in male it is XY.
(3) Autosomal recessive trait can only be expressed in homozygous condition and both parents must carry the recessive allele in order to express it.Both male and female are affected with equal frequency.
(4) Sex linked recessive trait can be expressed even in presence of a single allele as most of the sex linked genes are present on X Chromosome for example:- genes responsible for color blindness and haemophilia. Males have only one X Chromosome. A single recessive gene on that X Chromosome will express the trait.So male is more affected than female.Hope it helps.
(2) Sex linked traits are governed by genes on sex Chromosomes. example in humans there is one pair of sex Chromosomes, in female it is XX and in male it is XY.
(3) Autosomal recessive trait can only be expressed in homozygous condition and both parents must carry the recessive allele in order to express it.Both male and female are affected with equal frequency.
(4) Sex linked recessive trait can be expressed even in presence of a single allele as most of the sex linked genes are present on X Chromosome for example:- genes responsible for color blindness and haemophilia. Males have only one X Chromosome. A single recessive gene on that X Chromosome will express the trait.So male is more affected than female.Hope it helps.
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