Question

Difference between clemmenson reduction and wolf kishner reduction?
Very urgent

Answer 1

The Clemmensen Reduction allows the deoxygenation of aldehydes or ketones, to produce the corresponding hydrocarbon. ... The Clemmensen Reduction is complementary to the Wolff-Kishner Reduction, which is run under strongly basic conditions. Acid-labile molecules should be reduced by the Wolff-Kishner protocol.


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Answer 2

The basic difference is the medium as Clemenson is in acidic medium so if OH is present so it will be attacked too but in Wolf Kishner it is in basic medium so OH group can be saved which is sensitive but if there is halogen ester or amide group it will not tolerate the reaction