Biology, asked by aikanshkumar6644, 1 year ago

Difference between depolarizing and nondepolarizing muscle relaxants

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Answered by kiya7
3

If you meant depolarizing & non-depolarizing muscle relaxants, depolarizing muscle relaxants actively bind to the acetylcholine receptors & at the same time activates or depolarizes the receptor. Succinylcholine is the only drug in this class that is used by anesthesia providers today. The duration of action of succinylcholine is very short, and this short duration of action makes succinylcholine a useful drug in situations where muscle relaxation is needed for only a short time.


On the other hand, non-depolarizing muscle relaxants bind to acetycholine receptors in a reversible manner but they do not activate the receptor, in contrast to the previous category. This particular effect on acetylcholine receptors is the main difference between the two.

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