Question

Difference between gel permeation and gel filtration chromatography

Answer 1

Gel permeation chromatography (GPC) is a type of size exclusion chromatography (SEC). Typically, when an aqueous solution is used to transport the sample through the column, the technique is known as gel-filtration chromatography, versus the name gel permeation chromatography, which is used when an organic solvent is used as a mobile phase.