Question

Difference between hard gelatin and soft gelatin capsule

Answer 1

Capsules are solid drug dosage forms for oral administration that come in hard or soft shells in different sizes and shapes. The drug is enclosed inside a hard or a soft shell. The capsule shells are made of gelatin and other substances which disintegrate in the presence of digestive fluids and release the drug contents.

The differences in between soft and hard gelatin capsules are:

1. Soft gelatin capsules, also called as soft-gels are sealed hermetically as 1-piece capsules that contain a semi-solid or liquid fill, whereas hard gelatin capsules shell consists of two parts namely a body and a cap.

2. Hard gelatin capsules are cylindrical in shape while soft gelatin capsules are available in round, oval and tube-like shapes.

3. Soft gelatin contains gelatin, plasticizers, preservatives, colouring agents, sugars, flavouring agents, and opacifying agents, whereas hard gelatin capsules are prepared from gelatin, titanium dioxide, colouring agents and plasticizers.

4. The ratio of plasticizer and gelatin is more in a soft gelatin capsule (0.8 : 1) than in hard gelatin capsule (0.4 : 1).

5. Hard gelatin capsules are sealed after they are filled to ensure that the medicines do not come out of the capsule due to rough handling. Filling and sealing of soft gelatin capsules are done in a combined operation on machines.

Answer 2

A hard gelatin capsule is a type of capsule that is usually used to contain medicine in the form of dry powder or very small pellets. Oral medications include tablets and hard gelatin capsules that are filled with powder. Hard gelatin capsules are usually filled with powders, granules, or tiny pellets.

A hard gelatin capsule is a type of capsule that is usually used to contain medicine in the form of dry powder or very small pellets. Oral medications include tablets and hard gelatin capsules that are filled with powder. Hard gelatin capsules are usually filled with powders, granules, or tiny pellets.A softgel or soft gelatin capsule is a solid capsule (outer shell) surrounding a liquid or semi-solid center (inner fill). ... They are oral dosage form for medicine similar to capsules. Softgel shells are a combination of gelatin, water, opacifier and a plasticizer such as glycerin and/or sorbitol.

A hard gelatin capsule is a type of capsule that is usually used to contain medicine in the form of dry powder or very small pellets. Oral medications include tablets and hard gelatin capsules that are filled with powder. Hard gelatin capsules are usually filled with powders, granules, or tiny pellets.A softgel or soft gelatin capsule is a solid capsule (outer shell) surrounding a liquid or semi-solid center (inner fill). ... They are oral dosage form for medicine similar to capsules. Softgel shells are a combination of gelatin, water, opacifier and a plasticizer such as glycerin and/or sorbitol.____________________________________✰

A hard gelatin capsule is a type of capsule that is usually used to contain medicine in the form of dry powder or very small pellets. Oral medications include tablets and hard gelatin capsules that are filled with powder. Hard gelatin capsules are usually filled with powders, granules, or tiny pellets.A softgel or soft gelatin capsule is a solid capsule (outer shell) surrounding a liquid or semi-solid center (inner fill). ... They are oral dosage form for medicine similar to capsules. Softgel shells are a combination of gelatin, water, opacifier and a plasticizer such as glycerin and/or sorbitol.____________________________________✰ʜᴏᴘᴇ ᴛʜɪs ʜᴇʟᴘᴇᴅ