Difference between monoclonal antibody and poly clonal antibody
Answers
Antibodies are a type of globular proteins produced by the plasma B cells in response to a specific antigen. An antigen can be a foreign molecule that interacts with the cells of the immune system, triggering an immune response. The molecules on the antigens to which the antibodies attach themselves are called epitopes. The region of the antibody which binds to the epitope is called a paratope. Monoclonal antibodies and polyclonal antibodies are the two varieties of antibodies, which are used in therapeutics as well as in research applications. Both monoclonal and polyclonal antibodies interact with the same antigen. The main difference between monoclonal and polyclonal antibodies is that monoclonal antibodies are produced by the same clone of plasma B cells, and they bind to a unique epitope whereas polyclonal antibodies are produced by different clones of plasma B cells, and they bind to the different epitopes in the same antigen.