Difference between unit membrane model and fluid mosic model?
Answers
Overton (1895) suggested that the cell membranes contain lipids. This conclusion was based on the fact that fat solvents dissolved the membrane easily and fat soluble substances passed easily through the cell membranes. Some workers like Hober (1910) and Fricke (1925) found elow electrical conductivity in the cell membrane which indicated the presence of lipid layer.
Gorter and Grendel (1925)’ were the first to suggest a possible structure of the cell membrane. On the basis of studies of cell membranes of erythrocytes they showed that the lipid extracted from the red cell ghost spread in area twice that of a simple molecular film.
So it was thought that the membrane consisted of double layers of lipid molecules, the polar hydrophilic groups of the molecules being situated on the outside and hydrophobic ends standing at right angles to the surface are oriented inwardly