Question

Differences between leukemoid reaction and leukemia

Answer 1

As far as the blood picture is concerned, the difference between them is not readily appreciable.But there is a vast difference between the two.Leukemoid reactionoccurs in response to an inciting agent such as an infectious organism for the neutrophilsThe cells produced are polyclonal i.e. the cells which repliacte have different characteristics such as different antibody production or different sueface antibodyAt the genetic level, there is essentialy no differenceThe cellular replication halts on the elimination of the offending agent.Essentially a physiological response.Higher levels if neutrophil alkaline phosphatase in the neutrophilsWhile in LeukemiaThere is a mutation at the genetic level that predisposes to unlimited and useless replicationCells are monoclonal and all have very similar characteristics because usually all of them belong to one ancestor cellGenetically defective cells.Cwllular replication is directionless and the only way to halt it is to disrupt the replicatinf mechanismALWAYS A PATHOLOGICAL Response . Neoplastic, actually.Usually lower levels of NAP except CML (?)

Answer 2

Answer:

leucocytosis - increase in total leucocyte count mostly increases in bacterial and viral infection .

leukemia - abnormal increase of leucocyte which leads to blood cancer.