differentiate between active and resting stage of heart
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Effects of Temperature Changes
The cardiac AP is strongly changed by temperature (Fig. 4). Lowering of temperature increases the duration and reduces the rate of upstroke of cardiac AP. As a consequence, heart rate and velocity of impulse conduction over the heart are depressed, and the duration of contraction of each cardiac myocyte lasts longer. The longer duration of AP allows more time for calcium influx through the sarcolemma and at least partly compensates for the temperature-dependent decrease in calcium influx via ICa. Prolonged depolarization also allows more time for the myofilaments to generate force.
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