Differentiating general acid catalysis from specific acid catalysis
Answers
Answer:
In acid catalysis and base catalysis a chemical reaction is catalyzed by an acid or a base. The acid is the proton donor and the base is the proton acceptor, known as Brønsted-Lowry acid and base respectively. Typical reactions catalyzed by proton transfer are esterfications and aldol reactions. In these reactions the conjugate acid of the carbonyl group is a better electrophile than the neutral carbonyl group itself. Catalysis by either acid or base can occur in two different ways: specific catalysis and general catalysis. Many enzymes operate by acid-catalysis.
Explanation:
• A large fraction of chemical reactions and an even larger frac-tion of biochemical reactions involve the> C= 0 or> C= N-group. Many of these reactions, such as hydration of the car-bonyl group (eq 1), involve the reversible addition of a nucleo