difficulties face during measurement of drug release from microencapsulated system are due to
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Microcapsules continue to be of much interest in controlled release because of relative ease ... as variable thickness, porosity, and inertness also makes modeling of drug release difficult.
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Disadvantages of using the microencapsulation method for drug delivery are:
- The cost of production of microencapsulated drugs might be higher during manufacturing as compared to lab-scale production.
- It is difficult to reproduce and maintain the quality of such drugs.
- The effect of the environment on the polymer can differ in different places.
- If there is a change in pH, temperature, etc. the quality of the drug will be affected.
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