DiGeorge syndrome is characterized by a cleft palate, immune deficiency, and developmental issues. Which chromosomal change causes it?
Answers
The correct answer is Deletion.
DiGeorge syndrome generally referred to as 22q11.2 deletion syndrome. It signifies a disease arising when a small section of chromosome 22 gets missing. This deletion results in poor growth of various body systems.
The medical complications usually related with the syndrome comprise heart defects, poor immune function, delayed development with behavioral and emotional issues, a cleft palate, and complications related to the reduced calcium levels in the blood.
Deletion of chromosomal segment.
Deletion which is also called gene deletion, deficiency, or deletion mutation is a type of mutations(sign: Δ) a genetic aberration in which a part of a chromosome or a sequence of DNA is lost during DNA replication. Any number of nucleotides can be deleted, from a single base to an entire piece of chromosome sequence.