discribe the life cycle of plasmodium vivox in human 8 mrks
Answers
Answer:
P. vivax lifecycle (reproduced with permission from Lancet Infectious Diseases) - click to enlarge
The P. vivax lifecycle is complex, including more than ten stages of cellular differentiation, with the parasite invading at least four types of cells within two different hosts.
*Mosquito to human transmission
During a blood meal, a malaria-infected female Anopheles mosquito inoculates sporozoites into the human host.
*Hypnozoites
Undetectable with current diagnostic methods, hypnozoites in the human liver may reactivate weeks or months after the initial infection, leading to multiple clinical relapses and onward transmission.
*Asexual blood stage infection
Following their release into the blood, merozoites invade reticulocytes (immature red blood cells), and mature into schizonts which rupture to accelerate the infection. This asexual erythrocytic stage (or blood stage) causes the symptoms of malaria which appear about 48 h after infection