Question

Discuss modes of action of amino glycosides ?

Answer 1

Answer:

The mechanism of action of aminoglycosides depends on the inhibition of polypeptide synthesis. In fact, some of them such as Streptomycin, Sisomicin and Gentamicin are believed to cause codon misreading, by increasing the incorporation of certain aminoacids into polypeptide in the ribosome-polyribonucleotide system.

Answer 2

Answer:

The mechanism of action of aminoglycosides depends on the inhibition of polypeptide synthesis. In fact, some of them such as Streptomycin, Sisomicin and Gentamicin are believed to cause codon misreading, by increasing the incorporation of certain aminoacids into polypeptide in the ribosome-polyribonucleotide system.

Explanation:

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