discuss on the statement -telophase is reverse of prophase
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. The changes occurring in telophase are almost reverse to those which take place in late prophase.
. the daughter chromosomes arrived at the poles of the cells lengthen and their visibility decreases due to decondensation of chromatin.
. the kinetochore fibres disappear.
. the nuclear membrane re appears and nucleoli are reorganised.
. at the end of telophase two independent daughter nuclei are organised in the same mother cell.
. nuclear membrane, nucleolus, Golgi complexes, endoplasmic reticulum disappears. that's why telophase Is the reverse phase to prophase.
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Answer:
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At telophase of divisions when two daughter nuclei are formed, WRM-1 localized preferentially to the posterior than anterior nuclei (Takeshita & Sawa, 2005; Nakamura et al., 2005). This is in good contrast to its anterior cortical localization that is still observed during telophase. Photobleaching experiments revealed that WRM-1 in the anterior cytoplasm and nucleus as well as that in the posterior side accumulates in the posterior nucleus and that the nuclear export rates of WRM-1 are higher in the anterior nucleus. This nuclear asymmetry of WRM-1 is regulated by WRM-1 itself on the anterior cortex, as expression of WRM-1::CAAX that uniformly localized to the cortex inhibits WRM-1 localization in both nuclei (Mizumoto & Sawa, 2007a). Cortical WRM-1 recruits APR-1 to the anterior cortex. In apr-1 mutants, WRM-1 nuclear export is inhibited, resulting in its localization in both nuclei. Thus, APR-1 on the cortex mediates the effects of WRM-1 in the inhibition of WRM-1 nuclear localization.