Discuss the role of lymphoids in the immune response. Explain the different
types of lymphoid organs giving two examples of each type in human.
Answers
Explanation:
ᴛʜᴇ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs ᴀʀᴇ ᴛʜᴏsᴇ ᴏʀɢᴀɴs ᴡʜᴇʀᴇ ʟʏᴍᴘʜᴏᴄʏᴛᴇs ᴏʀɪɢɪɴᴀᴛᴇ, ᴍᴀᴛᴜʀᴇ ᴀɴᴅ ᴘʀᴏʟɪғᴇʀᴀᴛᴇ ғᴏʀ ʙᴏᴅʏ’s ɪᴍᴍᴜɴᴇ sʏsᴛᴇᴍ.
ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs ᴀʀᴇ ᴏғ ᴛᴡᴏ ᴛʏᴘᴇs:
ɪ. ᴘʀɪᴍᴀʀʏ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs
• ᴛʜᴇ ᴏʀɢᴀɴs ᴡʜᴇʀᴇ ʟʏᴍᴘʜᴏᴄʏᴛᴇs ᴏʀɪɢɪɴᴀᴛᴇ ᴀɴᴅ ᴍᴀᴛᴜʀᴇ ᴛᴏ ʙᴇᴄᴏᴍᴇ ᴀɴᴛɪɢᴇɴ-sᴇɴsɪᴛɪᴠᴇ, ᴇ.ɢ., ʙᴏɴᴇ ᴍᴀʀʀᴏᴡ ᴀɴᴅ ᴛʜʏᴍᴜs, ᴀʀᴇ ᴄᴀʟʟᴇᴅ ᴘʀɪᴍᴀʀʏ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs.
ᴀ. ʙᴏɴᴇ ᴍᴀʀʀᴏᴡ
• ɪᴛ ɪs ᴛʜᴇ ᴘʀɪᴍᴀʀʏ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴ ᴡʜᴇʀᴇ ᴀʟʟ ʙʟᴏᴏᴅ ᴄᴇʟʟs ɪɴᴄʟᴜᴅɪɴɢ ʟʏᴍᴘʜᴏᴄʏᴛᴇs ᴏʀɪɢɪɴᴀᴛᴇ.
• ʙᴏɴᴇ ᴍᴀʀʀᴏᴡ ᴘʀᴏᴠɪᴅᴇs ᴛʜᴇ ᴍɪᴄʀᴏ-ᴇɴᴠɪʀᴏɴᴍᴇɴᴛ ғᴏʀ ᴛʜᴇ ᴅᴇᴠᴇʟᴏᴘᴍᴇɴᴛ ᴀɴᴅ ᴍᴀᴛᴜʀᴀᴛɪᴏɴ ᴏғ ʙ-ʟʏᴍᴘʜᴏᴄʏᴛᴇs.
ʙ. ᴛʜʏᴍᴜs
• ᴛʜʏᴍᴜs ɪs ᴀ ʟᴏʙᴇᴅ ᴏʀɢᴀɴ ʟᴏᴄᴀᴛᴇᴅ ɴᴇᴀʀ ᴛʜᴇ ʜᴇᴀʀᴛ ᴀɴᴅ ʙᴇɴᴇᴀᴛʜ ᴛʜᴇ ʙʀᴇᴀsᴛʙᴏɴᴇ.
• ɪᴛ ɪs ǫᴜɪᴛᴇ ʟᴀʀɢᴇ ᴀᴛ ᴛʜᴇ ᴛɪᴍᴇ ᴏғ ʙɪʀᴛʜ ʙᴜᴛ ʀᴇᴅᴜᴄᴇs ᴡɪᴛʜ ᴀɢᴇ.
• ɪᴛ ᴘʀᴏᴠɪᴅᴇs ᴛʜᴇ ᴍɪᴄʀᴏ-ᴇɴᴠɪʀᴏɴᴍᴇɴᴛ ғᴏʀ ᴛʜᴇ ᴅᴇᴠᴇʟᴏᴘᴍᴇɴᴛ ᴀɴᴅ ᴍᴀᴛᴜʀᴀᴛɪᴏɴ ᴏғ ᴛ-ʟʏᴍᴘʜᴏᴄʏᴛᴇs.
ɪɪ. sᴇᴄᴏɴᴅᴀʀʏ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs
• ᴛʜᴇ ᴏʀɢᴀɴs ᴡʜᴇʀᴇ ʟʏᴍᴘʜᴏᴄʏᴛᴇs ɪɴᴛᴇʀᴀᴄᴛ ᴡɪᴛʜ ᴛʜᴇ ᴀɴᴛɪɢᴇɴ ᴀɴᴅ ᴘʀᴏʟɪғᴇʀᴀᴛᴇ ᴛᴏ ʙᴇᴄᴏᴍᴇ ᴇғғᴇᴄᴛᴏʀ ᴄᴇʟʟs, ᴇ.ɢ., sᴘʟᴇᴇɴ, ʟʏᴍᴘʜ ɴᴏᴅᴇs, ᴛᴏɴsɪʟs, ᴘᴇʏᴇʀ’s ᴘᴀᴛᴄʜᴇs ᴏғ sᴍᴀʟʟ ɪɴᴛᴇsᴛɪɴᴇ ᴀɴᴅ ᴀᴘᴘᴇɴᴅɪx ᴀʀᴇ ᴄᴀʟʟᴇᴅ sᴇᴄᴏɴᴅᴀʀʏ ʟʏᴍᴘʜᴏɪᴅ ᴏʀɢᴀɴs.
ᴀ. sᴘʟᴇᴇɴ
• ɪᴛ ɪs ᴀ ʟᴀʀɢᴇ ʙᴇᴀɴ-sʜᴀᴘᴇᴅ ᴏʀɢᴀɴ ᴀɴᴅ ᴄᴏɴᴛᴀɪɴs ʟʏᴍᴘʜᴏᴄʏᴛᴇs ᴀɴᴅ ᴘʜᴀɢᴏᴄʏᴛᴇs.
• ɪᴛ ᴀᴄᴛs ᴀs ᴀ ғɪʟᴛᴇʀ ᴏғ ᴛʜᴇ ʙʟᴏᴏᴅ ʙʏ ᴛʀᴀᴘᴘɪɴɢ ʙʟᴏᴏᴅ-ʙᴏʀɴᴇ ᴍɪᴄʀᴏᴏʀɢᴀɴɪsᴍs.
• ɪᴛ ʜᴀs ᴀ ʟᴀʀɢᴇ ʀᴇsᴇʀᴠᴏɪʀ ᴏғ ᴇʀʏᴛʜʀᴏᴄʏᴛᴇs.
ʙ. ʟʏᴍᴘʜ ɴᴏᴅᴇs
• ᴛʜᴇsᴇ ᴀʀᴇ sᴍᴀʟʟ sᴏʟɪᴅ sᴛʀᴜᴄᴛᴜʀᴇs ᴘʀᴇsᴇɴᴛ ᴀᴛ ᴅɪғғᴇʀᴇɴᴛ ᴘᴏɪɴᴛs ᴀʟᴏɴɢ ᴛʜᴇ ʟʏᴍᴘʜᴀᴛɪᴄ sʏsᴛᴇᴍ.
• ᴛʜᴇʏ ᴛʀᴀᴘ ᴛʜᴇ ᴍɪᴄʀᴏᴏʀɢᴀɴɪsᴍs ᴏʀ ᴏᴛʜᴇʀ ᴀɴᴛɪɢᴇɴs ᴛʜᴀᴛ ᴇɴᴛᴇʀ ᴛʜᴇ ʟʏᴍᴘʜ ᴀɴᴅ ᴛɪssᴜᴇ ғʟᴜɪᴅ.
• ᴀɴᴛɪɢᴇɴs ᴛʀᴀᴘᴘᴇᴅ ɪɴ ᴛʜᴇ ʟʏᴍᴘʜ ɴᴏᴅᴇs ᴀᴄᴛɪᴠᴀᴛᴇ ᴛʜᴇ ʟʏᴍᴘʜᴏᴄʏᴛᴇs ᴀɴᴅ ᴘʀᴏᴅᴜᴄᴇ ᴀɴ ɪᴍᴍᴜɴᴇ ʀᴇsᴘᴏɴsᴇ.
ᴄ. ᴍᴜᴄᴏsᴀʟ ᴀssᴏᴄɪᴀᴛᴇᴅ ʟʏᴍᴘʜᴏɪᴅ ᴛɪssᴜᴇ (ᴍᴀʟᴛ)
• ɪᴛ ɪs ғᴏʀᴍᴇᴅ ᴏғ ᴍᴀssᴇs ᴏғ ʟʏᴍᴘʜᴏɪᴅ ᴛɪssᴜᴇ ʟɪɴɪɴɢ ᴛʜᴇ ᴍᴜᴄᴏsᴀ ᴏғ ʀᴇsᴘɪʀᴀᴛᴏʀʏ, ᴅɪɢᴇsᴛɪᴠᴇ ᴀɴᴅ ᴜʀɪɴᴏɢᴇɴɪᴛᴀʟ ᴛʀᴀᴄᴛs.
• 50 ᴘᴇʀ ᴄᴇɴᴛ ᴏғ ᴛʜᴇ ʟʏᴍᴘʜᴏɪᴅ ᴛɪssᴜᴇ ɪɴ ʜᴜᴍᴀɴ ʙᴏᴅʏ ɪs ғᴏʀᴍᴇᴅ ʙʏ ᴍᴀʟᴛ.