discuss the two factors which affects the rate of nucleophilic substitution in an acid derivative
Answers
Answered by
0
Hiee....
=> Within a row – more electronegative atom => weaker nucleophile. Within a column, size of atom. Polar protic solvent, bigger atom is better; polar aprotic solvent, smaller atom is better. Resonance – if the nucleophilic lone pair can be delocalized by resonance, it will make it less nucleophilic.
Similar questions
Social Sciences,
1 month ago
English,
1 month ago
Math,
2 months ago
History,
2 months ago
Accountancy,
7 months ago
English,
7 months ago
Geography,
7 months ago