Discuss why genomes of most dna viruses are replicated in the nucleus and genomes of most rna viruses are replicated in cytoplasm
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Once the nucleocapsid of DNA virus enters the host cell, it proceeds to the nucleus where it mimics the genome of the host cell.
Usually, the viral genome is replicated using the host cell DNA polymerase, and the viral genome is transcribed by the host cell RNA polymerase.
The resulting transcripts carrying information encoding viral proteins is then transported to the cytoplasm and seen as a template by the host cell ribosomes. Some of these newly synthesized viral proteins are used as the protein capsid around newly replicated viral DNA molecules.
These new virions are released from the cell, where they target other host cells and trigger new rounds of infection.
As DNA viruses exploit the host cell machinery to complete their life cycles they carry small genomes encoding mostly viral structural proteins, like those for the capsid.
There are exceptions, notably the smallpox DNA virus encodes its own DNA replication machinery so it replicates in the cytoplasm.
Usually, the viral genome is replicated using the host cell DNA polymerase, and the viral genome is transcribed by the host cell RNA polymerase.
The resulting transcripts carrying information encoding viral proteins is then transported to the cytoplasm and seen as a template by the host cell ribosomes. Some of these newly synthesized viral proteins are used as the protein capsid around newly replicated viral DNA molecules.
These new virions are released from the cell, where they target other host cells and trigger new rounds of infection.
As DNA viruses exploit the host cell machinery to complete their life cycles they carry small genomes encoding mostly viral structural proteins, like those for the capsid.
There are exceptions, notably the smallpox DNA virus encodes its own DNA replication machinery so it replicates in the cytoplasm.
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