disease caused by growth harmone . please explain the diseases in 300 word .
Answers
HYPOPITUITARISM
Growth hormone deficiency is a complex problem that can take different forms from patient to patient.Growth hormone is a protein produced by the pituitary gland, which is located near the base of the brain and attached to the hypothalamus (a part of the brain that helps to regulate the pituitary gland). If the pituitary gland or the hypothalamus is malformed or damaged, it may mean that the pituitary gland can’t produce hormone.
If the pituitary gland is lacking in multiple pituitary hormones, the condition is called hypopituitarism.
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Explanation:
Growth hormone deficiency is a complex problem that can take different forms from patient to patient.
Causes
Damage to the pituitary gland or hypothalamus may be the result of an abnormal formation that occurred before your child was born (congenital) or something that occurred during or after birth (acquired).
Congenital growth hormone deficiency can occur if there are mutations in genes for factors that are important in pituitary gland development, or in receptors and factors (including growth hormone) along the growth hormone pathway; to date, however, the cause of most of these cases is unknown.
Acquired causes of growth hormone deficiency include:
a brain tumor in the hypothalamus or pituitary
head trauma
radiation therapy for cancers, if the treatment field includes the hypothalamus and pituitary
diseases that infiltrate the hypothalamus or its connection to the pituitary gland, such as histiocytosis
an autoimmune condition (lymphocytic hypophysitis)
It's also important to remember that growth hormone deficiency is only one of many conditions that may affect your child’s growth. Your child’s short stature may be caused by other syndromes, and growth failure may be due to decreased nutritional intake, gastrointestinal disorders, diseases that have increased metabolic demand or hypothyroidism.