DNA is soluble in water because the phosphate groups, the deoxyribose sugar and the nitrogenous bases are all soluble in water... The content of nucleoplasm is 90-92% water.... So why not the DNA is not getting dissolved in the nucleoplasm???
Answers
Answer: The nuclear envelope encloses the DNA and defines the nuclear compartment. This envelope consists of two concentric membranes that are penetrated by nuclear pore complexes (Figure 12-9). Although the inner and outer nuclear membranes are continuous, they maintain distinct protein compositions. The inner nuclear membrane contains specific proteins that act as binding sites for chromatin and for the protein meshwork of the nuclear lamina that provides structural support for this membrane. The inner membrane is surrounded by the outer nuclear membrane, which is continuous with the membrane of the ER. Like the membrane of the ER that will be described later in this chapter, the outer nuclear membrane is studded with ribosomes engaged in protein synthesis. The proteins made on these ribosomes are transported into the space between the inner and outer nuclear membranes (the perinuclear space), which is continuous with the ER lumen
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