Question

Dna supercoiling - a global transcriptional regulator for enterobacterial growth?

Answer 1

DNA transcriptase I think so

Answer 2

regulation of DNA supercoiling provides a coherent explanation for the main modes of transcriptional control — stringent control, growth-rate control and growth-phase control — during the normal growth of Escherichia coli.
An important aspect of growth control in enterobacteria is regulation of production of the translational machinery.