Chemistry, asked by ingalebhupen6990, 1 year ago

Does formation of mesylate why does chloride not react with mesylate

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Answered by Anonymous
5

It's relatively straightforward actually. We use “mesyl chloride” (MsCl) or “tosyl chloride” (TsCl), and the neutral alcohol performs a substitution reaction on sulfur, leading to formation of O-S and breakage of S-Cl. Then, deprotonation of the charged alcohol leads to the neutral mesylate or tosylate.

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