Drag each tile to the correct box. Order the events that occur during DNA replication.
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Answer:
Step 1: Replication Fork Formation
Before DNA can be replicated, the double stranded molecule must be “unzipped” into two single strands. DNA has four bases called adenine (A), thymine (T), cytosine (C) and guanine (G) that form pairs between the two strands. Adenine only pairs with thymine and cytosine only binds with guanine. In order to unwind DNA, these interactions between base pairs must be broken. This is performed by an enzyme known as DNA helicase. DNA helicase disrupts the hydrogen bonding between base pairs to separate the strands into a Y shape known as the replication fork.
Step 2: Primer Binding
The leading strand is the simplest to replicate. Once the DNA strands have been separated, a short piece of RNA called a primer binds to the 3' end of the strand. The primer always binds as the starting point for replication. Primers are generated by the enzyme DNA primase.
Step 3: Elongation
Enzymes known as DNA polymerases are responsible creating the new strand by a process called elongation. There are five different known types of DNA polymerases in bacteria and human cells.
Step 4: Termination
Once both the continuous and discontinuous strands are formed, an enzyme called exonuclease removes all RNA primers from the original strands. These primers are then replaced with appropriate bases. Another exonuclease “proofreads” the newly formed DNA to check, remove and replace any errors.
Hope it helps
DNA Replication begins at the Origin of Replication.DNA polymerase attaches post primase to DNA nucleotides and move along towards the Replication Fork in 5 prime --> 3 Prime direction. It adds nucleotides to the half DNA molecules.
1. Helicase Unwind the parents DNA strand...✏️✏️✏️✏️✏️
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